Clean: “PI, VAL!” = Phenylalanine (the one-letter abbreviation is F, not P), Isoleucine, Valine, Alanine, Leucine.Clean: “ Tyr to Tri P Pheyllis (because she smells bad)” = Tyrosine, Try ptophan, Phenylalanine.Image: visualize a w Asp Glued to a “minus” sign = Glutamate (glutamic acid) and Aspartate (aspartic acid).Clean: “ Lysten!” “ K.” = one-letter abbreviation for lysine is K.Dirty: “ Hot Little Ass” = Histidine, Lysine, Arginine.
Clean: “ Good God, Father Frank Did Go Buy Pricey Pumpkin Pies”.Dirty: “ Genius Guys Finger Freely Dumb Guys Buy Pricey Pussy Pumps”.Molecules in glycolysis (G-glucose, G-glucose-6-phosphate, F-fructose-6-phosphate, F-fructose-1,6-bisphosphate, D-DHAP, G-glyceraldehyde-3-phosphate, B-1,3-bisphosphoglycerate, P-3-phosphoglycerate P-2-phosphoglycerate, P-PEP, P-pyruvate).Dirty: Sex For Fun = FADH2 produced in between Succinate & Fumarate.Dirty: G Spot for Sex = GTP produced in between Succinyl-CoA & Succinate.Clean: “ 3 New Girl Friends” = net of 3 NADH, 1 GTP, 1 FADH2.Dirty: “ 3 Naked Guys (or Girls) Fucking” = net of 3 NADH, 1 GTP, 1 FADH2.Clean: “ Collared Central Intelligence Agent Spoke Slander For Money”.Enzymes in the TCA Cycle (C-Citrate synthatase, C- Cis -aconitase, I- Isocitrate dehydrogenase, A-α-ketogluturate dehydrogenase, S-Succinyl CoA synthetase, S-Succinate dehydrogenase, F- Fumarase, M-Malate dehydrogenase).Clean: “ Can I Keep Selling Shells For Money, Officer?”.Dirty: “ Can I Keep Selling Sex For Money, Officer?”.Dirty: “ Cindy Is Kinky So She Fornicates More Often”.Dirty: “ PAh, Cindy is Always Sucking Some Flaccid Male Organ!”.Molecules in the TCA Cycle (C-citrate, I-, A-α-ketoglutarate, S-succinyl CoA, S-succinate, F-fumarate, M-malate, O-oxaloacetate).(If your interest has been piqued, I also recommend reading Moonwalking with Einstein, one of my favorite books.) Contents: If you’re unfamiliar with mnemonic devices, read this Wikipedia article for a primer. Please direct all concerns and suggestions to the Contact page. Recognition of the common structural properties linking distinct cytokine domains to some AMPs (both natural and designed) offers the potential for the production of useful new small molecules to treat a number of disease conditions by modulating imbalances in cellular responses that lead to pathology.Note: these mnemonics contain overt references to sex and drug use as well as profanity, which some readers might find offensive. Ubiquitous smaller natural molecules also exist that exhibit unique antimicrobial activities (lytic peptides/antimicrobial peptides, LPs/AMPs). It is known that some cytokines also possess direct antimicrobial activity thus representing an additional component to the evolutionary endowed armamentarium that aids multicellular organisms in their constant battle against pathogens. Their actions can be thought of as either autocrine or paracrine acting directly upon the same type of cell that secretes it and/or cells that reside in close proximity. They are, in effect, the messengers promoting desired interactions by communicating the signals between cells and tissues, thereby causing an adjustment of their behavior ensuring proper temporal and spatial responses. Cytokines play key roles in cell-signaling pathways.